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吕强
发布人: liuxin 点击次数:4313次 发布时间:2014-03-11 20:56:34

 

 

             吕强,1978年4月出生,教授、博士生导师。

          本科1999年毕业于青岛大学,

          2002年硕士研究生毕业于北京理工大学,

          2007年博士研究生毕业于清华大学,

          2007-2009年在美国Tufts大学David Kaplan研究组进行博士后研究,

          2009年11月进入现代丝绸国家工程实验室(苏州)工作至今。

          现兼任中国材料研究学会理事和中国材料研究学会青年委员会理事。

 

2009年底回国后已主持省部级以上项目5项,企业合作项目1项,其中包括国家自然科学基金面上项目1项,教育部博士点基金1项,江苏省教育厅高校重大基础科学项目1项,教育部归国留学基金1项,企业合作攻关项目1项,作为学术骨干参加973项目1项,总经费约250万,在国内外知名刊物Biomaterials,Biomacromolecules,Acta Biomaterialia,Macromolecular Bioscience等已发表SCI研究论文36篇,申请国家发明专利8项。

 

 研究方向: 丝蛋白纳米组装,丝蛋白生物材料

 

近五年承担的科研项目:

1.丝蛋白基肛瘘修补塞的开发(横向项目,150万)

2.丝蛋白三维微纳结构的构建及其对细胞生长和分化的作用(国家自然科学基金面上项目,63万)

3.具有骨诱导性的仿生功能性丝蛋白人工骨的构建(江苏省教育厅高校基础研究重大项目,7.5万)

4.纳米化丝素蛋白调控碳酸钙生物矿化的机制研究( 教育部博士点新教师基金,3.6万)

5.保持生长因子活性的丝蛋白多孔支架制备和应用(教育部归国留学人员启动基金,4.2万)

6.干细胞与丝蛋白生物材料在仿生功能性皮肤构建及其运用中的作用机制(973项目子课题,50万,课题子方向负责人)

 

近五年发表的代表性论文论著专利等:

1.Qiang Lu*, Hesun Zhu, Cencen Zhang, Feng Zhang, Bing Zhang, David L Kaplan*, Silk-assembly mechanism and control-from thermodynamics to kinetics. Biomacromolecules,2012, 13, 826-832.
2.Feng Zhang, Baoqi Zuo,Zhihai Fan, Zonggang Xie, Qiang Lu*, Xueguang Zhang*. Mechanisms and control of silk-based electrospinning. Biomacromolecules,2012,13,798-804.
3.Xingliang He, Xiaowei Huang, Qiang Lu*, Shuling Bai*, Hesun Zhu, Nanoscale control of silks for regular hydroxyapatite formation. Progress in Natural science: Materials International(In press).
4.Aili Zhang, Yu Tu, Songbing Qin, Yan Li, Juying Zhou, Na Chen, Qiang Lu, Bingbo Zhang, Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. Journal of Colloid and Interface Science, 2012, 372, 239-244.
5.Qiang Lu*, Xiaoqin Wang, Hesun Zhu, David L Kaplan. Surface immobilization of antibody on silk fibroin through conformational transition.Acta Biomaterialia, 2011, 7, 2782-2786.
6.Qiang Lu*, Yongli Huang, Mingzhong Li, Baoqi Zuo, Shenzhou Lu, Jiannan Wang, Hesun Zhu, David L Kaplan. Silk fibroin electrogelation mechanisms. Acta Biomaterialia, 2011, 7, 2394-2400.
7.Qiang Lu*, Bing Zhang, Mingzhong Li, Baoqi Zuo, David L Kaplan, Yongli Huang, Hesun Zhu. Degradation Mechanism and control of silk fibroin, Biomacromolecules, 2011, 12, 1080-1086.
8.Qiang Lu*, Xiuli Wang, Shenzhou Lu, Mingzhong Li, David L Kaplan, Hesun Zhu, Nanofibrous architecture of silk fibroin scaffolds prepared with a mild self-assembly process, Biomaterials, 2011, 32, 1059-1067.
9.黄永利,吕强*,李明忠*,张冰,朱鹤孙,电场调控载药丝素蛋白微球的制备,科学通报,2011,56, 1013-1018.
10.Qiang Lu, Xiaoqin Wang, Xiao Hu, Peggy Cebe, Fiorenzo Omenetto, David L Kaplan. Stabilization and release of enzymes from silk films. Macromolecular Bioscience, 2010,10, 359-368.
11.Qiang Lu, Xiaohui Zhang, Xiao Hu, David L Kaplan. Green process to prepare silk/gelatin biomaterial scaffolds. Macromolecular Bioscience, 2010, 10, 289-298.
12.Qiang Lu, Xiao Hu, Xiaoqin Wang, Jonathan A Kluge, Shenzhou Lu, Peggy Cebe, David L Kaplan. Water-insoluble silk films with silk I structure. Acta Biomaterialia, 2010, 6, 1380-1387.
13.Xiao Hu, Qiang Lu, Lin Sun, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David L Kaplan. Biomaterials from ultrasonication-induced silk fibroin-hyaluronic acid hydrogels. Biomacromolecules, 2010, 11, 3178-3188.
14.Gary G Leisk, Tim J Lo, Tuna Yucel, Qiang Lu, David L Kaplan. Electrogelation for protein adhesives. Advanced Materials, 2010, 21, 711-715.
15.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiaohui Zhang, Jonathan A Kluge, Neha Uppal, Fiorenzo Omenetto, David L Kaplan. Insoluble and flexible silk films containing glycerol. Biomacromolecules, 2010, 11, 143-150.
16.Xiaoqin Wang, Tuna Yucel, Qiang Lu, Xiao Hu, David L Kaplan. Silk nanospheres and microspheres from silk/pva blend films for drug delivery, Biomaterials, 2010, 31, 1025-1035.
17.Xiao Hu, Qiang Lu, David L Kaplan, Peggy Cebe. Microphase separation controlled β-sheet crystallization kinetics in fibrous proteins. Macromolecules, 2009, 42, 2079-2087.
18.Qiang Lu, Kun Hu, Qingling Feng, Fuzhai Cui. Growth of fibroblast and vascular smooth muscle cells in fibroin/collagen scaffold. Materials Science and Engineering C, 2009, 29, 2239-2245.
19.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiao Hu, Neha Uppal, Fiorenzo G Omenetto, David L Kaplan. Stabilization of enzymes in silk films.Biomacromolecules, 2009, 10, 1032-1042.
20.Qiang Lu, Qingling Feng, Kun Hu, Fuzhai Cui. Preparation of three-dimensional fibroin/collagen scaffolds in various pH conditions. Journal of Materials Science-Materials in Medicine, 2008, 19, 629-634.
21.Qiang Lv, Kun Hu, Qingling Feng, Fuzai Cui. Fibroin/collagen hybrid hydrogels with crosslinking method: preparation, properties, and cytocompatibility. Journal of Biomedical Mateirals Research Part A, 2008, 84A, 198-207.
22.Kun Hu, Fuzai Cui, Qiang Lu, Jun Ma, Qingling Feng. Preparation of fibroin/recombinant human-like collagen scaffold to promote fibroblasts compatibility. Journal of Biomedical Materials Research Part A, 2008, 84A, 483-490.
23.Qiang Lu, Kun Hu, Qingling Feng, Fuzai Cui. Preparation of insoluble fibroin/collagen films without methanol treatment and the increase of its flexibility and cytocompatibility. Journal of Applied polymer Science, 2008, 109, 1577-1584.
24.Qiang Lu, Shejia Zhang, Kun Hu, Qingling Feng, Chuanbao Cao, Fuzhai Cui. Cytocompatibility and blood compatibility of multifunctional fibroin/collagen/heparin scaffolds. Biomaterials, 2007, 28, 2306-2313.
25.Qiang Lv, Kun Hu, Qingling Feng, Fuzhai Cui, Chuanbao Cao. Preparation and characterization of PLA/fibroin composite and culture of HepG2 (human hepatocellular liver carcinoma cell line) cells. Composites Science and Technology, 2007, 67, 3023-3030.
26.K Hu, Q Lv, FZ Cui, L Xu, YP Jiao, Y Wang, QL Feng, HL Wang, LY Huang. A novel poly(L-lactide) (PLLA)/fibroin hybrid scaffold to promote hepatocyte viability and decrease macrophage responses. Journal of Bioactive and Compatible Polymers, 2007, 22, 395-410.

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